Discussion: Cellular Adaptation NUR 315

Discussion: Cellular Adaptation NUR 315

Discussion: Cellular Adaptation

Explain at least two types of cellular damage that are largely responsible for progression from reversible to irreversible cellular injury.

In your responses to peers, discuss the most common type of cellular injury occurring within the human body.

To complete this assignment, review the  document.

Cellular injury “leads to injury of tissues and organs ultimately determining the structural patterns of disease” according to McCance and Huether (2019, p.49). Injury can be caused by numerous things including hypoxia, toxicity, immune reactions, or even genetics. When a cell is injured it can either recover, which would be reversible injury, or it can die which is irreversible injury (McCance and Huether).

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An example cellular injury that can start as reversible but ultimately lead to irreversible damage is, of course, hypoxia. McCance and Huether explain hypoxia as the lack of oxygen needed for the cell and is the most common form of cellular injury caused by many things including decreased hemoglobin, respiratory disease, or simply lack of oxygen in the air. For example, a patient experiencing a NSTEMI in in the stage where cellular injury can be reversible. There is still a blockage to some extent, which intermittently causes ischemia to the cells, but hasn’t yet evolved into a full-blown heart attack. A STEMI has now progressed to a fully blocked artery causing death to cells as they have no blood flow. If left to long untreated to much heart muscle may become permanently ischemic resulting in cell death and ultimately patient death. It only takes 1 minute of interrupted flow to the heart for it to weaken and become less efficient and 3-5 minutes for the affected area of the heart to no longer work (McCance and Huether).

Another example of cellular injury that can lead to irreversible damage is caused by chemicals. Being from NH where we have cold winters I was intrigued by McCance and Huether’s section regarding indoor air pollution from solid fuels like wood for open fires. If homes aren’t well ventilated it can cause an increased risk for particles and carbon monoxide poisoning. According to McCance and Huether, “several studies have found that long-term particulate matter air pollution exposure is associated with cardiovascular disease (CVD) morbidity and mortality (p61). It would make sense that repeat exposure to harsh chemicals eventually cause cell damage and then death as exposure continues.

Discussion: Cellular Adaptation Reference

McCance, K. L., & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in     adults and children (8th Ed.). St. Louis, MO: Elsevier.

Discussion Rubric: Undergraduate: Discussion: Cellular Adaptation

Your active participation in the discussion forums is essential to your overall success this term. Discussion questions are designed to help you make meaningful connections between the course content and the larger concepts and goals of the course. These discussions offer you the opportunity to express your own thoughts, ask questions for clarification, and gain insight from your classmates’ responses and instructor’s guidance.

Requirements for Discussion Board Assignments
Students are required to post one initial post and to follow up with at least two response posts for each discussion board assignment.

For your initial post (1), you must do the following:
• Compose a post of one to two paragraphs.
• In Module One, complete the initial post by Thursday at 11:59 p.m. Eastern Time.
• In Modules Two through Eight, complete the initial post by Thursday at 11:59 p.m. of your local time zone.
• Take into consideration material such as course content and other discussion boards from the current module and previous modules, when appropriate (make sure you are using proper citation methods for your discipline when referencing scholarly or popular resources).

For your response posts (2), you must do the following:
• Reply to at least two different classmates outside of your own initial post thread.
• In Module One, complete the two response posts by Sunday at 11:59
p.m. Eastern Time.
• In Modules Two through Eight, complete the two response posts by Sunday at 11:59 p.m. of your local time zone.
• Demonstrate more depth and thought than simply stating that “I agree” or “You are wrong.” Guidance is provided for you in each discussion prompt. Discussion: Cellular Adaptation

Rubric

Critical Elements Exemplary Proficient Needs Improvement Not Evident Value
Comprehension Develops an initial post with an organized, clear point of view or idea using rich and significant detail
(100%) Develops an initial post with a point of view or idea using adequate organization and
detail (85%) Develops an initial post with a point of view or idea but with some gaps in organization and
detail (55%) Does not develop an initial post with an organized point of view or idea (0%) 40
Timeliness Submits initial post on time
(100%) Submits initial post one day late
(55%) Submits initial post two or more
days late (0%) 10
Engagement Provides relevant and meaningful response posts with clarifying
explanation and detail (100%) Provides relevant response posts with some explanation
and detail (85%) Provides somewhat relevant response posts with some
explanation and detail (55%) Provides response posts that are generic with little
explanation or detail (0%) 30
Writing (Mechanics) Writes posts that are easily understood, clear, and concise using proper citation methods where applicable with no errors in
citations (100%) Writes posts that are easily understood using proper citation methods where applicable with few errors in
citations (85%) Writes posts that are understandable using proper citation methods where applicable with a number of
errors in citations (55%) Writes posts that others are not able to understand and does not use proper citation methods where applicable (0%) 20. Discussion: Cellular Adaptation
Total 100%

ADDITIONAL INSTRUCTIONS FOR THE CLASS

Discussion Questions (DQ)

  • Initial responses to the DQ should address all components of the questions asked, include a minimum of one scholarly source, and be at least 250 words.
  • Successful responses are substantive (i.e., add something new to the discussion, engage others in the discussion, well-developed idea) and include at least one scholarly source.
  • One or two sentence responses, simple statements of agreement or “good post,” and responses that are off-topic will not count as substantive. Substantive responses should be at least 150 words.
  • I encourage you to incorporate the readings from the week (as applicable) into your responses.

Weekly Participation

  • Your initial responses to the mandatory DQ do not count toward participation and are graded separately.
  • In addition to the DQ responses, you must post at least one reply to peers (or me) on three separate days, for a total of three replies.
  • Participation posts do not require a scholarly source/citation (unless you cite someone else’s work).
  • Part of your weekly participation includes viewing the weekly announcement and attesting to watching it in the comments. These announcements are made to ensure you understand everything that is due during the week.

APA Format and Writing Quality

  • Familiarize yourself with APA format and practice using it correctly. It is used for most writing assignments for your degree. Visit the Writing Center in the Student Success Center, under the Resources tab in LoudCloud for APA paper templates, citation examples, tips, etc. Points will be deducted for poor use of APA format or absence of APA format (if required).
  • Cite all sources of information! When in doubt, cite the source. Paraphrasing also requires a citation.
  • I highly recommend using the APA Publication Manual, 6th edition.

Use of Direct Quotes

  • I discourage overutilization of direct quotes in DQs and assignments at the Masters’ level and deduct points accordingly.
  • As Masters’ level students, it is important that you be able to critically analyze and interpret information from journal articles and other resources. Simply restating someone else’s words does not demonstrate an understanding of the content or critical analysis of the content.
  • It is best to paraphrase content and cite your source.

 

LopesWrite Policy

  • For assignments that need to be submitted to LopesWrite, please be sure you have received your report and Similarity Index (SI) percentage BEFORE you do a “final submit” to me.
  • Once you have received your report, please review it. This report will show you grammatical, punctuation, and spelling errors that can easily be fixed. Take the extra few minutes to review instead of getting counted off for these mistakes.
  • Review your similarities. Did you forget to cite something? Did you not paraphrase well enough? Is your paper made up of someone else’s thoughts more than your own?
  • Visit the Writing Center in the Student Success Center, under the Resources tab in LoudCloud for tips on improving your paper and SI score.

Late Policy

  • The university’s policy on late assignments is 10% penalty PER DAY LATE. This also applies to late DQ replies.
  • Please communicate with me if you anticipate having to submit an assignment late. I am happy to be flexible, with advance notice. We may be able to work out an extension based on extenuating circumstances.
  • If you do not communicate with me before submitting an assignment late, the GCU late policy will be in effect.
  • I do not accept assignments that are two or more weeks late unless we have worked out an extension.
  • As per policy, no assignments are accepted after the last day of class. Any assignment submitted after midnight on the last day of class will not be accepted for grading.

Communication

  • Communication is so very important. There are multiple ways to communicate with me: 
    • Questions to Instructor Forum: This is a great place to ask course content or assignment questions. If you have a question, there is a good chance one of your peers does as well. This is a public forum for the class.
    • Individual Forum: This is a private forum to ask me questions or send me messages. This will be checked at least once every 24 hours.

 

 

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