SIGNATURE ASSIGNMENT: LECTURIO REFLECTION AND ANALYSIS
Lecturio Reflection and Analysis Signature Assignment
Hypertensive disorders of pregnancy, vein and lymphatic pathologies, and liver cirrhosis may present with one or more similar symptoms. Below we compare their clinical manifestations, risk factors, differentials, diagnosis, and management recommendations.
Lecturio Series | |||
Hypertensive Disorders of Pregnancy | Vein and Lymphatic Pathology | Liver Cirrhosis | |
Clinical Manifestations | -Headaches
-Edema -Proteinuria (greater than 0.3g/24 hours) -high blood pressure (greater than 140/90mmHg) -Visual disturbances |
-Edema
-Enlarged swollen, knotted purple veins -Itchy skin above affected veins -Skin discoloration -weakness of affected limb or area |
-Edema and ascites
-Yellowing of skin and eyes (jaundice) -Palmar erythema -Easy bruising and prolonged clotting time -Hypogonadism |
Risk Factors | -Obesity
-Family history of hypertension -Pre-existing hypertension -Multiple fetuses (twins, triplets) -African-American race |
-Obesity
-Female gender -Pregnancy -Infections such as filariasis, lymphangitis -Medications such as oral contraceptives |
-Alcohol intake
-Hepatitis infection -Obesity -Type 2 diabetes -Long-term treatment with corticosteroids |
Differentials | -Hyperaldosteronism
-Chronic kidney disease -Preeclampsia |
-Renal failure
-Heart failure -Hypothyroid myxedema -Hematoma -Cellulitis |
-Viral hepatitis
-Pericarditis -Malignancy -Congenital hepatic fibrosis -Budd-Chiari syndrome |
Management | -Timely delivery or immediate delivery in preeclampsia
-IV hydralazine -IV labetalol -Oral nifedipine |
-Control body weight
-Anticoagulant medication such as warfarin -Sclerotherapy for varicose veins -NSAIDs such as Ibuprofen |
-IV fluids to maintain blood pressure
-lifestyle modifications such as quitting smoking and alcohol use -Diuretics -Beta-blockers such as propranolol to manage variceal bleeding |
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Below we compare their transmission factors and pathophysiology, primary medical and psychosocial concerns, and implications for critical care and advanced practice nurses.
Hypertensive Disorders of Pregnancy | Vein and Lymphatic Pathology, such as lymphadenopathy
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Liver Cirrhosis
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Transmission Factors | -Pre-existing hypertension
-Diabetes -Kidney disease |
-Infectious processes such as via filarial worms
-Autoimmune immune processes |
-Hepatitis B and C infections
-Chronic alcohol abuse -Obesity and diabetes |
Pathophysiology | Surges of estrogen and progesterone result in vasodilation. Plasma blood volume expands, resulting in increased heart rate. Elevated heart rate and stroke volume increase cardiac output (Wilkerson,2019). | -This condition results from sustained elevated blood pressure within the veins, resulting in leakage of blood contents into adjacent tissue. In lymphatic failure, this mechanism is compromised, resulting in fluid accumulation within the lymphatic system. | It occurs due to the destruction of liver architecture by fibrous bands around regenerative nodules, resulting in vascular injury and biliary obstruction and causing hepatocyte injury and death.
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Primary medical concerns | Risk for development of eclampsia, HELLP syndrome, or chronic hypertension. | Patient risks complications such as cellulitis, superior vena cava syndrome, tracheal and bronchial obstruction. | Patients develop complications over time, such as portal hypertension, liver failure, and hepatocellular carcinoma (Ye,2022). |
Primary psychosocial concerns | Patients show higher levels of depression and anxiety | -physical effects may interfere with one’s lifestyle and work
-Body image and esteem issues may develop |
-Patients may develop stress, depression, and anxiety due to fear of the progression of the disease and increased dependence on their caregivers
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Implications for critical care and advanced practice nurses | -Management helps prevent progression to severe hypertension and maternal complications such as heart failure. | -Detailed physical history and clinical exams need to be conducted to determine the cause of the pathology and rule out malignancies or undetected allergies and infectious processes. | -Healthcare providers give support and guidance for the management of alcohol abuse
-Assessment of other associated comorbidities such as diabetes and obesity. |
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References
Wilkerson, R. G., & Ogunbodede, A. C. (2019). Hypertensive disorders of pregnancy. Emergency Medicine Clinics of North America, 37(2), 301–316. https://doi.org/10.1016/j.emc.2019.01.008
Ye, F., Zhai, M., Long, J., Gong, Y., Ren, C., Zhang, D., Lin, X., & Liu, S. (2022, July 12). The burden of liver cirrhosis in mortality: Results from the global burden of disease study. Frontiers, 10. https://doi.org/10.3389/fpubh.2022.909455
ONLY DO PART 2!
Compose a 300-400 word analysis of the related conditions. Compare three or more related conditions in the following areas: clinical manifestations, risk factors, differentials, diagnosis, and management/treatment recommendations. Next, answer the questions below. Use the table in the submittal form Download submittal formto organize this information.
What are the transmission and pathophysiology of the conditions?
What are the primary medical concerns for patients with these conditions?
What might be the primary psychosocial concerns for patients with these conditions?
What are the implications of these conditions for critical care and advanced practice nurses?
Assignment Guidelines:
Use the Lecturio Reflection and Analysis Assignment Submittal Form Download Lecturio Reflection and Analysis Assignment Submittal Formfor this assignment. If you choose to complete the assignment in a different document, include the quiz screenshots at the beginning or the end.
Include references to at least two scholarly research articles and evidence-based guidelines.
Use the Current APA Style to format your paper and cite your sources. Your source(s) should be integrated into the paragraphs. Use internal citations pointing to evidence in the literature and supporting your ideas. You will need to include a reference page listing those sources. Cite a minimum of three resources.